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Cannabidiol has been explored as an alternative for pain relief and anti-inflammation due to its high safety and low adverse effects profiles. Countless studies have identified the potent, yet safe therapeutic components of CBD. Below, you can see the safety profile comparison between cannabidiol and acetaminophen.
» Pain Relief, Without The Pain
In human studies, CBD administration did not induce side effects across a wide range of dosages, including acute and chronic dose regimens, and tolerance to CBD did not develop. Learn more about CBD and its effectiveness towards pain relief and inflammation HERE.
CBD does not interfere with several psychomotor and psychological functions in humans. CBD does not affect heart rate, blood pressure, or performance in the verbal paired-associate learning test as measured by recall score at doses up to 600mg.
Effects On Memory:
Short-term memory and other cognitive deficits have been reported in humans after smoking marijuana. In rats tested against a delayed match to sample task, THC showed a correlation between delay and dose-dependent behavioral deficit produced in this task. This performance was selectively impaired by a lack of discharge of hippocampal neurons. However, CBD at doses of 0.75-2.0mg/kg bw (i.p.) were tested in the same task and no significant effect on performance was observed.
Effects on Physiological Parameters:
Several studies administering CBD by different routes have shown it to be safe, in regards to the effects on physiological parameters. It is important to note that the lack of CBD side effects was observed during studies whose primary objectives were not to evaluate CBD´s safety, but to study cannabinoid activity. Furthermore, several other studies that evaluated the anxiolytic effects of CBD in rodents demonstrated the safety and tolerability of this drug in rodents.
Chronic oral administration of 10mg CBD daily for 21 days did not induce any changes in neurological (including electroencephalogram (EEG)), clinical (including electrocardiogram (EKG)), psychiatric, blood or urine examinations. Likewise, oral CBD administration in healthy participants (3mg/kg bw daily for 30 days) and in epileptic patients (200-300mg daily for 135 days) was well tolerated and no signs of toxicity or serious side effects were detected on neurological and physical examinations, blood and urine analysis, or EKG and EEG, which were performed at weekly intervals.
Tylenol Get The Facts:
- Data compiled by the U.S. Food and Drug Administration
- Tylenol uncommon side effects