January 29, 2015

Pain Relief

» Get The Facts

Cannabidiol has been explored as an alternative for pain relief and anti-inflammation due to its high safety and low adverse effects profiles. Countless studies have identified the potent, yet safe therapeutic components of CBD. Below, you can see the safety profile comparison between cannabidiol and acetaminophen.


  • Tylenol Safety Profile

    The active ingredient in Tylenol, acetaminophen, accounts for more than 100,000 calls to poison centers, roughly 60,000 emergency-room visits and hundreds of deaths each year in the United States.
    Data compiled by the U.S. Food and Drug Administration has linked as many as 980 deaths in a year to drugs containing acetaminophen.
  • Tylenol & Liver Damage

    Tylenol overdose is the leading cause of acute liver failure in the United States, and the drug in some cases led to fatalities.
    In England, it is the leading cause of liver failure requiring transplants. In 2009, the FDA issued guidelines for adding overdose guidelines to packages and in 2011, the agency confirmed the link between the drug and liver damage.
  • Acetaminophen Effects

    Read about some of the more uncommon side effects that have been reported from acetaminophen.
    •Bloody or black tarry stools •Bloody/Cloudy Urine •Skin Rash •Hives/Itching •Sores •Ulcers •Unusual Bleeding/Bruising •Unusual Tiredness/Weakness •Fever With or Without Chills (not present before treatment)
  • Safety of Cannabidiol

    Several studies suggest that CBD is well tolerated and safe in humans at high doses and with chronic use.
    Studies administering CBD by different routes have shown it to be safe, in regards to the effects on physiological parameters.


» Pain Relief, Without The Pain

cbd pain relief

In human studies, CBD administration did not induce side effects across a wide range of dosages, including acute and chronic dose regimens, and tolerance to CBD did not develop. Learn more about CBD and its effectiveness towards pain relief and inflammation HERE

Acute Studies:
CBD does not interfere with several psychomotor and psychological functions in humans. CBD does not affect heart rate, blood pressure, or performance in the verbal paired-associate learning test as measured by recall score at doses up to 600mg.

Effects On Memory:
Short-term memory and other cognitive deficits have been reported in humans after smoking marijuana. In rats tested against a delayed match to sample task, THC showed a correlation between delay and dose-dependent behavioral deficit produced in this task. This performance was selectively impaired by a lack of discharge of hippocampal neurons. However, CBD at doses of 0.75-2.0mg/kg bw (i.p.) were tested in the same task and no significant effect on performance was observed.

Effects on Physiological Parameters: 
Several studies administering CBD by different routes have shown it to be safe, in regards to the effects on physiological parameters. It is important to note that the lack of CBD side effects was observed during studies whose primary objectives were not to evaluate CBD´s safety, but to study cannabinoid activity. Furthermore, several other studies that evaluated the anxiolytic effects of CBD in rodents demonstrated the safety and tolerability of this drug in rodents.

Chronic Studies:
Chronic oral administration of 10mg CBD daily for 21 days did not induce any changes in neurological (including electroencephalogram (EEG)), clinical (including electrocardiogram (EKG)), psychiatric, blood or urine examinations. Likewise, oral CBD administration in healthy participants (3mg/kg bw daily for 30 days) and in epileptic patients (200-300mg daily for 135 days) was well tolerated and no signs of toxicity or serious side effects were detected on neurological and physical examinations, blood and urine analysis, or EKG and EEG, which were performed at weekly intervals.


Tylenol Get The Facts:

  1. http://www.drugwatch.com/tylenol/
  2. Data compiled by the U.S. Food and Drug Administration
  3. Tylenol uncommon side effects


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