A review of CBD trials exploring possible treatment for Parkinson’s Disease appeared in the 1/31/19 issue of European Archives of Psychiatry and Clinical Neuroscience. Though the abstract stresses that more large scale random controlled trials are needed, CBD was found in the studies reviewed to have a “therapeutic effect in non-motor symptoms” of Parkinson’s Disease. In another study CBD aided in “reductions on levodopa-induced dyskinesia”. Levodopa is a Parkinson’s drug, and dyskinesia is the medical term for involuntary movements or twitches common in Parkinson’s patients. The abstract also points to studies that found CBD had “neuroprotective effects”. The Journal of Clinical Science defines neuroprotection as “an effect that may result in salvage, recovery or regeneration of the nervous system, its cells, structure and function”
The Journal of Pancreatic Cancer also published a literature review of CBD studies in its 1/25/19 issue. Lab tests showed “antiproliferative and proapoptotic effects”. Apoptosis is programmed cell death, in this case of cancer cells. Lab studies also “consistently demonstrated tumor growth-inhibiting effects with CBD, THC, and synthetic derivative”. It stresses that no human clinical trials of pancreatic cancer patients have been conducted.
A study published in the 1/31/19 issue of Drug Metabolism Reviews pointed to cannabinoids as a “future treatment for bone regeneration”. The abstract explained that cannabinoids act on CB-1 and CB-2 receptors in our endocannabinoid system, and that CB-2 receptors are found at higher levels in bone cells. Cannabinoids can also act through a CB-1 agonist to inhibit “osteroclast differentation” which is basically bone degradation.
Studies like these are emerging every day as more and more governments are legalizing hemp, marijuana, and the medicine we can extract from it. The possibilities of CBD are amazing and we can only be optimistic about further research. That it is relatively inexpensive and widely available is another positive.
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